PERUBAHAN STRUKTUR HISTOLOGIS INSANG DAN HATI IKAN NILA (Oreochromis niloticus Linnaeus 1758) YANG TERPAPAR MERKURI
Abstract
Penelitian ini bertujuan untuk mengkaji perubahan struktur histologis organ insang, hati dan ginjal ikan nila akibat dari paparan merkuri. Penelitian dilakukan dari bulan Februari hingga Juni 2013. Ikan nila berukuran panjang 11-13 cm dengan bobot rata-rata 20 gram dipaparkan pada konsentrasi sub kronik merkuri klorida (0,164 mgL-1) selama 56 hari. Pembuatan preparat histologis hati dan dilakukan dengan metode histoteknik menggunakan pewarnaan Haemotoxylin dan Eosin. Hasil penelitian menunjukkan adanya pengaruh negatif pada hati dan ginjal ikan nila akibat dari paparan merkuri. Paparan merkuri pada organ insang menyebabkan terjadinya perubahan struktur histologis berupa perbesaran sel organ (hypertrophy), penambahan jumlah sel (hyperplasia) pembengkokan lamela sekunder (curling of secondary lamella), penghimpitan lamella sekunder (fusion in secondary lamella) dan kematian sel (neukrosis). Perubahan histologis pada organ hati berupa perbesaran sel organ (hypertrophy), penambahan jumlah sel (hyperplasia), penciutan inti sel (shrinkage of hepatocytes), pendarahan (hemorage), dan kematian sel (neukrosis).
Kata kunci: merkuri klorida, histologis, hypertrophy, hyperplasia, neukrosis.
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